Sulforaphane Attenuates Gentamicin-Induced Nephrotoxicity: Role of Mitochondrial Protection

Figure 9

SFN prevents the GM-induced increase in active caspase-9. Representative figures are shown in (b–e) and the isotype control is shown in (a). There is an evident increase in the active caspase-9 immunostaining in (d) GM group compared to (b) CT and (c) SFN groups. The treatment with SFN in the (e) SFN + GM group reduced the caspase-9 activation (40x). (f) Quantification was made by using integrated optical density (IOD) values. Data are mean±SEM. ^∗𝑃<0.01 versus CT; ^#𝑃<0.05 versus GM.

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