Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts

<table>Effect of treatment on tumour growth. (a) The effect of JIN, JIN + DDP, and DDP on tumour size. Tumour volumes were measured every 3 days. (b) The effect of JIN, JIN + DDP, and DDP on tumour weight. Data presented are the mean ± SD at 8–25 days posttumour implantation; groups were compared and analysed using <i>t</i>-test. <svg height="13.95" id="M19" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> tumor weight compared with model group, <svg height="15.775" id="M20" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 67.387497 15.775" width="67.387497" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> tumor volume compared with model group. DDP, JIN, and coformula inhibited tumor weight by 63.99%, 55.03%, and 65.79%, respectively, (<svg height="11.375" id="M21" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>) after 15 days of treatment compared to mice administered the vehicle only.</table>

Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts 