Research Article

Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts

Table 4

Genes regulated more than 2 folds by JIN + DDP treatment in H460 cells.

GeneBankSymbolDescriptionJIN + DDP/MOCK value

NM_000076CDKN1CCyclin-dependent kinase inhibitor 1C (p57, Kip2)3.240.003
NM_001904CTNNB1Catenin (cadherin-associated protein), beta 1, 88 kDa0.260.003
NM_005228EGFREpidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)0.460.05
NM_001429EP300E1A binding protein p3000.350.007
NM_005252FOSV-fos FBJ murine osteosarcoma viral oncogene homolog0.460.03
NM_002133HMOX1Hemeoxygenase (decycling) 10.420.09
NM_005526HSF1Heat shock transcription factor 10.440.02
NM_002467MYCV-myc myelocytomatosis viral oncogene homolog (avian)0.220.0008
NM_003738PTCH2Patched homolog 2 (Drosophila)0.400.01
NM_003202TCF7Transcription factor 7 (T-cell specific, HMG-box)0.320.006
NM_015626WSB1WD repeat and SOCS box-containing 10.13