Low Frequency Electroacupuncture Alleviated Spinal Nerve Ligation Induced Mechanical Allodynia by Inhibiting TRPV1 Upregulation in Ipsilateral Undamaged Dorsal Root Ganglia in Rats

Figure 5

TRPV1 agonist 6′-IRTX blocked the antiallodynic effect of 2 Hz EA. 6′-IRTX was intraperitoneally injected 10 min before 2 Hz EA treatment on day 15. Data are presented as mean ± SEM, 𝑛=8 per group. ^∗𝑃<0.05, ^∗∗∗𝑃<0.001, SNL + EA + 0.001 mg/kg 6′-IRTX group or SNL + EA + 0.01 mg/kg 6′-IRTX group versus SNL + EA + vehicle group; ^#𝑃<0.05, SNL + EA + 0.01 mg/kg 6′-IRTX group versus SNL + EA + 0.001 mg/kg 6′-IRTX group.

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