Research Article
Populus balsamifera Extract and Its Active Component Salicortin Reduce Obesity and Attenuate Insulin Resistance in a Diet-Induced Obese Mouse Model
Table 3
Effects of obesity, P. balsamifera, and salicortin treatments on hepatic and muscular triglyceride accumulation.
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The colorimetric dosage of TG levels in both the liver and muscle was determined using a commercial kit (Randox Laboratories ltd). Measurements were obtained after 16 weeks of treatment with either standard diet (Chow), HFD (DIO), and for the last 8 of the 16 weeks with HFD in combination with P. balsamifera at 125 or 250 mg/kg, or with the active salicortin at 12.5 mg/kg. All values are expressed as percentage of respective Chow (reference set at 100%) and represent the mean ± SEM. The number of animals for each group for the P. balsamifera protocol was: CHOW (); DIO (); P. balsamifera 125 (); P. balsamifera 250 (); and for the salicortin protocol: CHOW (); DIO (); salicortin (). †denotes DIO significantly different as compared to Chow (unpaired Student’s t test; P < 0.05). *denotes significantly different as compared to respective DIO (one way ANOVA, Bonferroni post hoc test; P < 0.05). denotes significantly different as compared to respective DIO (unpaired Student’s t test; P < 0.05). |