Research Article

Triptolide-Mediated Apoptosis by Suppression of Focal Adhesion Kinase through Extrinsic and Intrinsic Pathways in Human Melanoma Cells

Figure 1

Effect of TPL on viability of melanoma cells. (a) Human melanoma cell lines, SK-MEL-2 and SK-MEL-28, and B16F10 mouse melanoma cells were treated with various concentrations of TPL for 24 h. (b) Time-dependent effect of TPL on SK-MEL-2 cell growth after treatment of 50 nM TPL. Cell growth was measured by MTT assay. Data were presented as percentage of control and were mean ± SEM ( ).
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(a)
172548.fig.001b
(b)