Research Article

Brain Responses to Acupuncture Are Probably Dependent on the Brain Functional Status

Figure 3

Demonstration of the group analysis results of the normal, early, later, and recovered groups ( , , corrected with the Monte Carlo method). In the normal group, the activated brain areas spread over the whole brain, including lobule IX (A1), middle cingulate gyrus (A2), Rolandic operculum (A3), parahippocampal gyrus (A4), lobule IX (A5), insula (A6), parahippocampal gyrus (A7), inferior frontal gyrus (A8), inferior temporal gyrus (A9), lobule IX (A10), lobule III (A11), insula (A12), lobule VIIIa (A13), lobule VIIIb (A14), supramarginal gyrus (A15), lingual gyrus (A16), superior temporal gyrus (A17), lobule VIIa (A18), and postcentral gyrus (A19). In the early group, the activated areas became only a few, including lobule IX (B1 and B4), lingual gyrus (B2), and middle cingulate gyrus (B6), and there appeared deactivated areas in the middle frontal gyrus (B3) and inferior temporal gyrus (B5). In the later group, the activated areas became more obvious and more intense than those in the normal group which were shown in lobule VIIa (C1), superior temporal gyrus (C2), fusiform gyrus (C3), lobule VI (C4), lingual gyrus (C5), middle temporal gyrus (C6), culmen of cerebellum (C7), lobule VI (C8), posterior cingulate gyrus (C9), thalamus (C10), parahippocampal gyrus (C11), lingual gyrus (C12), fusiform gyrus (C13), inferior frontal gyrus (C14), fusiform gyrus (C15), insula (C16), middle temporal gyrus (C17), lobule VI (C18), vermis of the cerebellum (C19), lobule VI (C20), and middle cingulate gyrus (C21). In the recovered group, no activated areas were found above the threshold ( , ).
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(a) Normal group 
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(b) Early group
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(c) Later group
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(d) Recovered group