Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats
Figure 6
The effects of baicalin (0.90 g/kg, once daily for 7 days) on the expression of CYP3A2 in the rat liver. (a) Western blotting results. (b) Statistical analysis of western blotting results. CYP3A2 expression was measured using specific anti-rat CYP3A2 antibodies. GAPDH was used as the control for the normalisation of CYP3A2 density. Bars represent the mean ± SD of the fold change relative to the values in the control group (). Statistical significance is indicated as **, compared to control.
