Research Article

Yueju Pill Rapidly Induces Antidepressant-Like Effects and Acutely Enhances BDNF Expression in Mouse Brain

Figure 2

A rapid antidepressant-like behavioral responses by Yueju in the learned helpless paradigm. (a) Learned helplessness was quantified as number of escape failures in an active avoidance test. Mice received inescapable shock training for two days prior to a 30-trial active avoidance test. Escape failures were decreased in mice given Yueju (YJ). (b) The mean percent shock-elicited freezing for the entire observation period was also reduced in mice given YJ. , two-tailed t-test. Data represent mean ± SEM. .
184367.fig.002a
(a)
184367.fig.002b
(b)