Yueju Pill Rapidly Induces Antidepressant-Like Effects and Acutely Enhances BDNF Expression in Mouse Brain
Figure 4
BDNF expression at 30 minutes and 24 hours after an acute administration of Yueju. (a) BDNF and BDNF precursor (pro-BDNF) protein expression levels in mouse hippocampus were determined by Western blot at 30 minutes after treatment with Yueju (YJ) or ketamine (KET). For BDNF, one-way ANOVA, ; . For pro-BDNF, one-way ANOVA, ; . (b) BDNF and pro-BDNF protein expression levels at 24 hours after drug treatment. For BDNF, one-way ANOVA, ; . For pro-BDNF, one-way ANOVA, ; . (c) BDNF mRNA expression was examined by quantitative RT-PCR in mouse hippocampus at 30 min after drug treatment. One-way ANOVA, ; . *; **, compared with the control group (CTL). Data represent mean ± SEM. .
