Suppressions of Migration and Invasion by Cantharidin in TSGH-8301 Human Bladder Carcinoma Cells through the Inhibitions of Matrix Metalloproteinase-2/-9 Signaling

Figure 6

Cantharidin suppresses the activities of matrix metalloproteinases (MMPs) in TSGH-8301 cells. Gelatin zymography was used to evaluate the activities of MMP-2 and MMP-9 as described in Section 2. The different activity of MMP-2 and -9 was determined by densitometry analysis, and results are expressed as % of control. Similar results were obtained from three independent experiments.