Korean Red Ginseng Extract Attenuates 3-Nitropropionic Acid-Induced Huntington’s-Like Symptoms

Figure 5

Suppression of the 3-NP-induced microglial activation, but not astrocyte, by KRGE preadministration. Striatal sections were stained with anti-Iba-1 (a–h) or anti-GFAP (i–p) antibodies 24 hours after 3-NP administration without and with KRGE preadministration (250 mg/kg/day, p.o.).(a–h) 3-NP-induced microglial activation was inhibited by KRGE preadministration. Panels (e–h) and (m–p) display high magnification micrographs of panels (a–d) and (i–l) marked with squares, respectively. Scale bar = 50 μm.

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