| | Type | Cells/tissues | Effects | Reference |
| | In vitro research | rCMECs | PI3K/Akt pathway,
ERK upstream. |
Blanc et al., 2003 [32] | | H9C2 | TAB1-P38 apoptosis signaling pathway,
cell activity,
reduce sub-G1,
inhibit p38 phosphorylation,
interaction of TAB1 and P38. |
Du et al., 2010 [34] | | INS-1 | Phosphorylation of p38,
phosphorylation of JNK,
expression of Nrf2-HO-1,
expression of SIRT-1,
caspase-3 apoptotic pathway. |
Han et al., 2011 [36] | | PC12 | Expression of Par-4,
superoxide radicals scavenging,
xanthine oxidase inhibitory activity. |
Tang and Zhang, 2002 [37] | | HL-60 | Superoxide radicals-induced apoptosis,
xanthine/xanthine oxidase reactions. |
Liu et al., 2009 [38] | | Rabbit neointimal cell | Expression of p53,
frequency of TUNEL-positive cells. |
Hung et al., 2001 [39] |
| | Type | Organ/animals | Effects | Reference |
| | In vivo research | Rat heart | Myocardial infarct size,
blood lactate dehydrogenase. |
Du et al., 2010 [34] | | Rat heart | Cardiac function,
myocardial tissue structure,
expression of 36 kinds of proteins,
ADP-ribose polymerase-1 pathway,
integrity of mitochondria,
integrity of nuclei. |
Xu et al., 2011 [35] | | Rat heart | ST segment level,
serum creatine kinase-MB,
lactate dehydrogenase,
alanine aminotransferase,
cardiac troponin T content,
activities of superoxide dismutase, activities of catalase,
activities of glutathione peroxidase,
expression of anti-apoptotic protein, expression of Bcl-2,
expression of proapoptotic protein, expression of Bax. |
Yang et al., 2010 [40] |
|
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