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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 256782, 11 pages
http://dx.doi.org/10.1155/2013/256782
Research Article

Predicting the Drug Safety for Traditional Chinese Medicine through a Comparative Analysis of Withdrawn Drugs Using Pharmacological Network

1Shanghai Key Laboratory of New Drug Design, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
2Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

Received 5 March 2013; Accepted 7 April 2013

Academic Editor: Aiping Lu

Copyright © 2013 Mengzhu Xue et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Table S1: Key network topology property functions planted in Cytoscape and CentiBin.

Table S2: Summary for the 66 withdrawn drugs from DrugBank.

Table S3: Decisions and side effect records on approved drugs with similarity measurements more than 0.7 to withdrawn ones by same targets.

Table S4: Natural Products from the in-house TCM database with similarity values more than 0.7 to withdrawn drugs.

  1. Supplementary Material