Table 1: The general network topology analysis on the withdrawn drug-target network and the approved drug-target network by Cytoscape.

Topology propertiesWithdrawn drug-target networkApproved drug-target network

Clustering coefficient0.00.0
Connected components44217
Network diameter723
Network radius11
Network centralization0.1070.054
Shortest paths29025673774
Characteristic path length2.9147.510
Avg. number of neighbors1.8493.801
Number of nodes1722889
Number of drug nodes661411
Network density0.0110.001
Network heterogeneity1.3451.874
Isolated nodes23 (34.85%)131 (9.28%)
Number of self-loops00
Multiedge node pairs00