In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria
Table 3
Percentage of apoptotic cells (%).
Cell lines
Compounds
12.5 μg/mL
25 μg/mL
40 μg/mL
50 μg/mL
MCF-7
Curzerenone
4.83 ± 0.58a
5.83 ± 0.76a
53.00 ± 2.2b
57.33 ± 4.65b
Alismol
6.17 ± 0.58a
9.17 ± 1.5b
43.00 ± 1.0d
29.63 ± 1.1c
Ca Ski
Curzerenone
4.82 ± 0.59a
7.89 ± 1.77b
39.67 ± 1.89c
54.67 ± 1.76d
Alismol
8.83 ± 0.58a
53.67 ± 1.76d
41.67 ± 0.76c
32.67 ± 1.04b
HCT-116
Curzerenone
45.00 ± 0.5a
50.00 ± 0.5b
46.5 ± 1.44a
49.17 ± 1.4b
Alismol
48.83 ± 1.61b
55.33 ± 3.01b
21.33 ± 2.02a
19.00 ± 0.87a
Values expressed are mean ± standard deviation (SD) of triplicate measurements. For the compounds with the different concentration, means in the same rows with different letters (a–d) were significantly different ().