Research Article

In Vitro Morphological Assessment of Apoptosis Induced by Antiproliferative Constituents from the Rhizomes of Curcuma zedoaria

Table 3

Percentage of apoptotic cells (%).

Cell linesCompounds12.5 μg/mL25 μg/mL40 μg/mL50 μg/mL

MCF-7Curzerenone4.83 ± 0.58a5.83 ± 0.76a53.00 ± 2.2b57.33 ± 4.65b
Alismol6.17 ± 0.58a9.17 ± 1.5b43.00 ± 1.0d29.63 ± 1.1c

Ca SkiCurzerenone4.82 ± 0.59a7.89 ± 1.77b39.67 ± 1.89c54.67 ± 1.76d
Alismol8.83 ± 0.58a53.67 ± 1.76d41.67 ± 0.76c32.67 ± 1.04b

HCT-116Curzerenone45.00 ± 0.5a50.00 ± 0.5b46.5 ± 1.44a49.17 ± 1.4b
Alismol48.83 ± 1.61b55.33 ± 3.01b21.33 ± 2.02a19.00 ± 0.87a

Values expressed are mean ± standard deviation (SD) of triplicate measurements. For the compounds with the different concentration, means in the same rows with different letters (a–d) were significantly different ( ).