Table 1: (a) Effect of HAOP and MOP pretreatment on aspirin + pylorus ligation-induced gastric lesions in rats. (b) Effect of HAOP and MOP posttreatment on aspirin + pylorus ligation-induced gastric lesions in rats.
(a)

Pretreatment Dose (mg/kg) Ulcer index Protection (%)

Aspirin + pylorus ligated control 4.39 ± 0.04 a*
Ranitidine 50 mg/kg/p.o 1.53 ± 0.02 a*b*65.14
MOP 100 mg/kg/p.o 1.03 ± 0.009 b*c*76.53
HAOP 100 mg/kg/p.o 0.82 ± 0.007 a*b*c*81.32

(b)

Posttreatment Dose (mg/kg) Ulcer index Protection (%)

Aspirin + pylorus ligated control 4.39 ± 0.04 a*
Ranitidine 50 mg/kg/p.o 1.53 ± 0.02 a*b*65.14
MOP 100 mg/kg/p.o 2.01 ± 0.02 a*b*c*54.21
HAOP 100 mg/kg/p.o 1.75 ± 0.02 a*b*c*60.13

The following values are expressed as mean ± SEM of 6 animals.
Comparisons were made between.
a: Group I versus II, III, IV, V, VI, and VII.
b: Group II versus III, IV, V, VI, and VII.
c: Group III versus V and VII.
Symbols represent statistical significance: * , # , @ .