(a) Proposed mechanism for the protective effects of carvacrol against hepatic steatosis in mice. Carvacrol decreased the expression of genes and phosphorylation of protein involved in lipogenesis, whereas it increased the expression of genes and phosphorylation of proteins involved in fatty acid oxidation in the livers of HFD-fed mice. (b) Schematic overview of cholesterol homeostasis and the effects of carvacrol in the livers of HFD-fed mice. Carvacrol lowers cholesterol content by reversing the HFD-induced downregulation of genes involved in cholesterol homeostasis. (c) Schematic overview of the genes regulated by carvacrol in TLR2- and 4-signaling pathway.