Research Article

Propolis Induces Chondroitin/Dermatan Sulphate and Hyaluronic Acid Accumulation in the Skin of Burned Wound

Figure 4

Dynamics of the sulfate disaccharide profile alterations in CS/DS chains from healing wounds (postburn days 3rd, 5th, 10th, 15th, and 21st) treated with propolis (a), AgSD (b), propolis vehicle (c), and NaCl (d). Day 0—normal skin. Disaccharides were released from CS/DS by chondroitinase ABC and subjected to reverse-phase HPLC after labeling with fluorophore 2-aminoacridone as described in Section 2.
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