Roots of Erigeron annuus Attenuate Acute Inflammation as Mediated with the Inhibition of NF-κB-Associated Nitric Oxide and Prostaglandin E₂ production

Figure 3

Inhibition of LPS-inducible NO and PGE₂ by EER. (a) NO and (b) PGE₂ accumulations. Raw264.7 cells were treated with EER at the indicated doses for 1 h and continuously incubated with LPS (1 μg/mL) for the next 24 h. (c) TNF-α and IL-1β contents in culture medium. Raw264.7 cells were stimulated by LPS with or without 10 μg/mL EER for 24 h. Data represents the mean ± S.E.M. from four separate experiments (significant as compared with vehicle-treated control, ^∗∗𝑃<0.01; significant as compared with LPS alone, ^##𝑃<0.01). EERs: extract of Erigeron annuus roots.

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