About this Journal Submit a Manuscript Table of Contents
Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 297427, 10 pages
http://dx.doi.org/10.1155/2013/297427
Research Article

Roots of Erigeron annuus Attenuate Acute Inflammation as Mediated with the Inhibition of NF-κB-Associated Nitric Oxide and Prostaglandin E2 production

1Medical Research Center for Globalization of Herbal Formulation, College of Oriental Medicine, Daegu Haany University, Daegu 706-828, Republic of Korea
2Department of Herbal Pharmaceutical Engineering, Daegu Haany University, Kyung-San, Kyung-Buk 712-715, Republic of Korea

Received 24 October 2012; Revised 10 January 2013; Accepted 15 January 2013

Academic Editor: Ke Ren

Copyright © 2013 Mi Jeong Jo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Mantovani, P. Allavena, A. Sica, and F. Balkwill, “Cancer-related inflammation,” Nature, vol. 454, no. 7203, pp. 436–444, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. G. Brevetti, G. Giugliano, L. Brevetti, and W. R. Hiatt, “Inflammation in peripheral artery disease,” Circulation, vol. 122, no. 18, pp. 1862–1875, 2010. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Hummasti and G. S. Hotamisligil, “Endoplasmic reticulum stress and inflammation in obesity and diabetes,” Circulation Research, vol. 107, no. 5, pp. 579–591, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. B. N. Lambrecht and H. Hammad, “The role of dendritic and epithelial cells as master regulators of allergic airway inflammation,” The Lancet, vol. 376, no. 9743, pp. 835–843, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Christaki, S. M. Opal, J. C. Keith et al., “Estrogen receptor β agonism increases survival in experimentally induced sepsis and ameliorates the genomic sepsis signature: a pharmacogenomic study,” Journal of Infectious Diseases, vol. 201, no. 8, pp. 1250–1257, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Bouffi, C. Bony, G. Courties, C. Jorgensen, and D. Noël, “IL-6-dependent PGE2 secretion by mesenchymal stem cells inhibits local inflammation in experimental arthritis,” PLoS ONE, vol. 5, no. 12, Article ID e14247, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. I. Posadas, M. Bucci, F. Roviezzo et al., “Carrageenan-induced mouse paw oedema is biphasic, age-weight dependent and displays differential nitric oxide cyclooxygenase-2 expression,” British Journal of Pharmacology, vol. 142, no. 2, pp. 331–338, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. C. C. Corriveau and R. L. Danner, “Endotoxin as a therapeutic target in septic shock,” Infectious Agents and Disease, vol. 2, no. 1, pp. 35–43, 1993. View at Scopus
  9. W. H. Watson, Y. Zhao, and R. K. Chawla, “S-adenosylmethionine attenuates the lipopolysaccharide-induced expression of the gene for tumour necrosis factor α,” Biochemical Journal, vol. 342, no. 1, pp. 21–25, 1999. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Kubes and D. M. McCafferty, “Nitric oxide and intestinal inflammation,” American Journal of Medicine, vol. 109, no. 2, pp. 150–158, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Kleinert, P. M. Schwarz, and U. Förstermann, “Regulation of the expression of inducible nitric oxide synthase,” Biological Chemistry, vol. 384, no. 10-11, pp. 1343–1364, 2003. View at Publisher · View at Google Scholar · View at Scopus
  12. Y. W. Kim, R. J. Zhao, S. J. Park et al., “Anti-inflammatory effects of liquiritigenin as a consequence of the inhibition of NF-κB-dependent iNOS and proinflammatory cytokines production,” British Journal of Pharmacology, vol. 154, no. 1, pp. 165–173, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. S. J. Kim, M. S. Ha, E. Y. Choi, J. I. Choi, and I. S. Choi, “Nitric oxide production and inducible nitric oxide synthase expression induced by Prevotella nigrescens lipopolysaccharide,” FEMS Immunology and Medical Microbiology, vol. 43, no. 1, pp. 51–58, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. Y. Kobayashi, “The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation,” Journal of Leukocyte Biology, vol. 88, no. 6, pp. 1157–1162, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Moncada, R. M. J. Palmer, and E. A. Higgs, “Nitric oxide: physiology, pathophysiology, and pharmacology,” Pharmacological Reviews, vol. 43, no. 2, pp. 109–142, 1991. View at Scopus
  16. S. G. Harris, J. Padilla, L. Koumas, D. Ray, and R. P. Phipps, “Prostaglandins as modulators of immunity,” Trends in Immunology, vol. 23, no. 3, pp. 144–150, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Ghosh and M. Karin, “Missing pieces in the NF-κB puzzle,” Cell, vol. 109, no. 2, pp. S81–S96, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. G. Bonizzi and M. Karin, “The two NF-κB activation pathways and their role in innate and adaptive immunity,” Trends in Immunology, vol. 25, no. 6, pp. 280–288, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. M. S. Hayden and S. Ghosh, “Signaling to NF-κB,” Genes and Development, vol. 18, no. 18, pp. 2195–2224, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. C. C. Bennington and D. A. Stratton, “Field tests of density- and frequency-dependent selection in Erigeron annuus (Compositae),” American Journal of Botany, vol. 85, no. 4, pp. 540–545, 1998. View at Scopus
  21. H. Oh, S. Lee, H. S. Lee et al., “Germination inhibitory constituents from Erigeron annuus,” Phytochemistry, vol. 61, no. 2, pp. 175–179, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. L. B. Katz, H. M. Theobald, R. C. Bookstaff, and R. E. Peterson, “Characterization of the enhanced paw edema response to carrageenan and dextran in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats,” Journal of Pharmacology and Experimental Therapeutics, vol. 230, no. 3, pp. 670–677, 1984. View at Scopus
  23. H. D. Kim, H. R. Cho, S. B. Moon et al., “Effect of exopolymers from Aureobasidium pullulans on formalin-induced chronic paw inflammation in mice,” Journal of Microbiology and Biotechnology, vol. 16, no. 12, pp. 1954–1960, 2006. View at Scopus
  24. R. L. C. Handy and P. K. Moore, “A comparison of the effects of L-NAME, 7-NI and L-NIL on caurageenan-induced hindpaw oedema and NOS activity,” British Journal of Pharmacology, vol. 123, no. 6, pp. 1119–1126, 1998. View at Publisher · View at Google Scholar · View at Scopus
  25. D. S. Jang, N. H. Yoo, N. H. Kim et al., “3,5-Di-O-caffeoyl-epi-quinic acid from the leaves and stems of Erigeron annuus inhibits protein glycation, aldose reductase, and cataractogenesis,” Biological and Pharmaceutical Bulletin, vol. 33, no. 2, pp. 329–333, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Y. Nam, S. J. Dae, L. Y. Jeong et al., “Erigeroflavanone, a flavanone derivative from the flowers of Erigeron annuus with protein glycation and aldose reductase inhibitory activity,” Journal of Natural Products, vol. 71, no. 4, pp. 713–715, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. M. S. Sung, Y. H. Kim, Y. M. Choi, H. M. Han, H. S. Jeong, and J. S. Lee, “Anti-inflammatory effect Erigeron annuus L. Flower extract though heme oxygenase-1 inhibition in Raw264.7 macrophages,” Journal of the Korean Society of Food Science and Nutrition, vol. 40, pp. 1507–1511, 2011.
  28. C. H. Jeong, H. R. Jeong, G. N. Choi, D. O. Kim, U. Lee, and H. J. Heo, “Neuroprotective and anti-oxidant effects of caffeic acid isolated from Erigeron annuus leaf,” Chinese Medicine, vol. 6, article 25, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Di Rosa, “Prostaglandins, leucocytes and non steroidal anti inflammatory drugs,” Polish Journal of Pharmacology and Pharmacy, vol. 26, no. 1-2, pp. 25–36, 1974. View at Scopus
  30. J. Garcia Leme, L. Hamamura, M. P. Leite, and M. Rocha e Silva, “Pharmacological analysis of the acute inflammatory process induced in the rat's paw by local injection of carrageenin and by heating,” British Journal of Pharmacology, vol. 48, no. 1, pp. 88–96, 1973. View at Scopus
  31. K. Omote, K. Hazama, T. Kawamata et al., “Peripheral nitric oxide in carrageenan-induced inflammation,” Brain Research, vol. 912, no. 2, pp. 171–175, 2001. View at Publisher · View at Google Scholar · View at Scopus
  32. M. J. Coffey, S. M. Phare, and M. Peters-Golden, “Induction of inducible nitric oxide synthase by lipopolysaccharide/interferon gamma and sepsis down-regulates 5-lipoxygenase metabolism in murine alveolar macrophages,” Experimental Lung Research, vol. 30, no. 7, pp. 615–633, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. E. Jimi and S. Ghosh, “Role of nuclear factor-κB in the immune system and bone,” Immunological Reviews, vol. 208, pp. 80–87, 2005. View at Scopus
  34. W. C. Huang, J. J. Chen, and C. C. Chen, “c-Src-dependent tyrosine phosphorylation of IKKβ is involved in tumor necrosis factor-α-induced intercellular adhesion molecule-1 expression,” Journal of Biological Chemistry, vol. 278, no. 11, pp. 9944–9952, 2003. View at Publisher · View at Google Scholar · View at Scopus
  35. S. A. Trushin, K. N. Pennington, E. M. Carmona et al., “Protein kinase Cα (PKCα) acts upstream of PKCθ to activate IκB kinase and NF-κB in T lymphocytes,” Molecular and Cellular Biology, vol. 23, no. 19, pp. 7068–7081, 2003. View at Publisher · View at Google Scholar · View at Scopus
  36. D. S. Jang, N. H. Yoo, Y. M. Lee, J. L. Yoo, Y. S. Kim, and J. S. Kim, “Constituents of the flowers of Erigeron annuus with inhibitory activity on the formation of advanced glycation end products (AGEs) and aldose reductase,” Archives of Pharmacal Research, vol. 31, no. 7, pp. 900–904, 2008. View at Publisher · View at Google Scholar · View at Scopus
  37. J. Nazaruk and D. Kalemba, “Chemical composition of the essential oils from the roots of Erigeron acris L. and Erigeron annuus (L.) Pers,” Molecules, vol. 14, no. 7, pp. 2458–2465, 2009. View at Publisher · View at Google Scholar · View at Scopus
  38. T. Iijima, Y. Yaoita, and M. Kikuchi, “Two new cyclopentenone derivatives and a new cyclooctadienone derivative from Erigeron annuus (L.) Pers., Erigeron philadelphicus L., and Erigeron sumatrensis Retz,” Chemical and Pharmaceutical Bulletin, vol. 51, no. 7, pp. 894–896, 2003. View at Scopus
  39. X. Li, M. Yang, Y. F. Han, and K. Gao, “New sesquiterpenes from Erigeron annus,” Planta Medica, vol. 71, no. 3, pp. 268–272, 2005. View at Publisher · View at Google Scholar · View at Scopus
  40. M. K. Jang, H. J. Lee, J. S. Kim, and J. H. Ryu, “A curcuminoid and two sesquiterpenoids from Curcuma zedoaria as inhibitors of nitric oxide synthesis in activated macrophages,” Archives of Pharmacal Research, vol. 27, no. 12, pp. 1220–1225, 2004. View at Scopus
  41. V. Hernández, M. D. C. Recio, S. Máñz, J. M. Prieto, R. M. Giner, and J. L. Ríos, “A mechanistic approach to the in vivo anti-inflammatory activity of sesquiterpenoid compounds isolated from Inula viscosa,” Planta Medica, vol. 67, no. 8, pp. 726–731, 2001. View at Scopus
  42. G. W. Hoyle, C. I. Hoyle, J. Chen, W. Chang, R. W. Williams, and R. J. Rando, “Identification of triptolide, a natural diterpenoid compound, as an inhibitor of lung inflammation,” American Journal of Physiology, vol. 298, no. 6, pp. L830–L836, 2010. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Navarro, B. de Las Heras, and A. M. Villar, “Andalusol, a diterpenoid with anti-inflammatory activity from Sideritis foetens Clemen,” Zeitschrift fü r Naturforschung. Section C, vol. 52, no. 11-12, pp. 844–849, 1997. View at Scopus
  44. D. T. A. Youssef, A. K. Ibrahim, S. I. Khalifa, M. K. Mesbah, A. M. S. Mayer, and R. W. M. Van Soest, “New anti-inflammatory sterols from the red sea sponges Scalarispongia aqabaensis and Callyspongia siphonella,” Natural Product Communications, vol. 5, no. 1, pp. 27–31, 2010. View at Scopus
  45. B. Singh, P. M. Sahu, and M. K. Sharma, “Anti-inflammatory and antimicrobial activities of triterpenoids from Strobilanthes callosus Nees,” Phytomedicine, vol. 9, no. 4, pp. 355–359, 2002. View at Scopus
  46. A. I. Huguet, M. Del Carmen Recio, S. Máez, R. M. Giner, and J. L. Ríos, “Effect of triterpenoids on the inflammation induced by protein kinase C activators, neuronally acting irritants and other agents,” European Journal of Pharmacology, vol. 410, no. 1, pp. 69–81, 2000. View at Publisher · View at Google Scholar · View at Scopus