Table 5: Methodological details of fMRI studies on BOLD responses for de-qi.

StudiesOne group analysis method value of a one group analysisTwo group analysis method value of a two group analysis

Studies that compared central BOLD responses between de-qi and sharp pain groups

Hui et al., 2000 [54]Kolmogorov-Smirnov test or (cor)
Hui et al., 2005 [33]group-averaged (unc), minimum 3 voxels
Hui et al., 2009 [55]group-averaged (unc), minimum 3 voxelstwo-sample unpaired t-tests (unc)
Sun et al., 2012 [40]random effect model (unc), minimum 5 voxelstwo-sample unpaired t-tests < 0.0001 (unc)

Studies where no subjects reported sharp pain/excluded subjects who experienced sharp pain from fMRI analysis

Napadow et al., 2005 [34]Fixed effect model (unc), minimum 3 voxels
Jeun et al., 2005 [78]random effect model (unc),
Kong et al., 2007 [79]random effect model (cor), minimum 10 voxels
Zhou and Jia 2008 [66]random effect model (cor) 50 voxels
Na et al., 2009 [80]random effect model (unc), minimum 100 voxels
Bai et al., 2010 [81]random effect model 5 (unc), minimum 5 voxels
Qiu et al., 2010 [82]random effect model (unc), minimum 3 voxels
Fang et al., 2012 [85]random effect model (cor), minimum 5 voxels
Sun et al., 2012 [40]random effect model (unc), minimum 5 voxels