Evidence of Antidepressive Effects of a Wakan-yaku, Hochuekkito, in Depression Model Mice with Learned-Helplessness Behavior

Figure 2

Phenotypic difference of mice in LH behavior test. The number of escape failures by the footshock-naïve control (open bars) and animals that had received inescapable footshock (closed bars) was analyzed. This diagram shows the distribution of the number of failures in this avoidance test. Animals that had received inescapable footshocks in the training session were classified into two groups: the LH group with failure scores no less than 10 as depressive mice and the non-LH group with failure scores no more than 5 as stress-resistant mice.