Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions
Figure 5
Immunohistochemical (IHC) staining of VEGF expression in lung tissues of the wild-type FVB mice, hVEGF- transgenic mice (Tg/Placebo), Tg/CM/Placebo, and Tg/CM/T1 groups. Tissues were taken from 10-month-old experimental mice after T1 or PBS administration for 4 months. Sections were stained with primary rabbit monoclonal antibody against human VEGF-A using a 1 : 40 working dilution. Upper panels were observed under 100x magnifications, and lower panels were observed under 200x magnifications.
