Active Component of Danshen (<i>Salvia miltiorrhiza</i> Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions

<table>Proposed mechanism of the T1 regulatory pathways in lung tumorigenesis of VEGF-A<sub>165</sub> overexpressed transgenic mice. The effects of T1 on lung tumor formation are hypothesized to occur through the cell cycle signaling. The diagram shows that T1 might inhibit the expressions of VEGF-A<sub>165</sub> during signal transduction, as well as reductions of Cyclin A and Cyclin B during S and G2/M cell cycle stages.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 8

Figure 8: Active Component of Danshen (<i>Salvia miltiorrhiza</i> Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions 

Figure 8 | Active Component of Danshen (Salvia miltiorrhiza Bunge), Tanshinone I, Attenuates Lung Tumorigenesis via Inhibitions of VEGF, Cyclin A, and Cyclin B Expressions 