Swertiamarin: An Active Lead from <i>Enicostemma littorale</i> Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-<i>γ</i> and Improves Insulin Sensitivity in Experimental NIDDM Rat Model

<table>Schematic representation of swertiamarin in amelioration of insulin resistance and TIIDM. Figure shows carbohydrate and fat metabolic pathways and candidate genes which are altered during diabetes. Swertiamarin treatment modulates not only the expression of these target genes which is marked in blue but also the metabolite levels in blood marked in red. </table>

Evidence-Based Complementary and Alternative Medicine

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Figure 10

Figure 10: Swertiamarin: An Active Lead from <i>Enicostemma littorale</i> Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-<i>γ</i> and Improves Insulin Sensitivity in Experimental NIDDM Rat Model 

Figure 10 | Swertiamarin: An Active Lead from Enicostemma littorale Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-γ and Improves Insulin Sensitivity in Experimental NIDDM Rat Model 