Swertiamarin: An Active Lead from <i>Enicostemma littorale</i> Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-<i>γ</i> and Improves Insulin Sensitivity in Experimental NIDDM Rat Model

<table>Change in body weight upon induction of diabetes and treatment of diabetic rats with EL, SM, and standard drug MFO. Data presented as mean ± SEM of 6 independent observations. <sup>##</sup><svg height="11.375" id="M5" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus control rats; **<svg height="11.375" id="M6" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus Diabetic rats.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 2

Figure 2: Swertiamarin: An Active Lead from <i>Enicostemma littorale</i> Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-<i>γ</i> and Improves Insulin Sensitivity in Experimental NIDDM Rat Model 

Figure 2 | Swertiamarin: An Active Lead from Enicostemma littorale Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-γ and Improves Insulin Sensitivity in Experimental NIDDM Rat Model 