Swertiamarin: An Active Lead from Enicostemma littorale Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-γ and Improves Insulin Sensitivity in Experimental NIDDM Rat Model
Figure 6
(a) Western blot study showing the effect of EL extract and SM treatments on the expression of insulin signaling proteins: IR and PI(3)K in the hepatic tissue as compared to diabetic rats. β-actin was taken as an internal control. (b) Immunoprecipitation study showing the effect of EL extract and SM treatments on the tyrosine phosphorylation of insulin signaling proteins: IR in the hepatic tissue as compared to diabetic rats (200 ug protein).