Research Article

Swertiamarin: An Active Lead from Enicostemma littorale Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-γ and Improves Insulin Sensitivity in Experimental NIDDM Rat Model

Figure 9

(a) Western blot study showing the effect of EL extract and SM treatments on the expression of insulin signaling proteins: IR and PI(3)K in the adipose tissue as compared to diabetic rats. β-actin was taken as an internal control. (b) Immunoprecipitation study showing the effect of EL extract and SM treatments on the phosphorylation of insulin signaling proteins: IR in the adipose tissue as compared to diabetic rats (100 ug protein).
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(a)
358673.fig.009b
(b)