Swertiamarin: An Active Lead from Enicostemma littorale Regulates Hepatic and Adipose Tissue Gene Expression by Targeting PPAR-γ and Improves Insulin Sensitivity in Experimental NIDDM Rat Model

Table 2

Lipid profile of control and treated diabetic rats.

Groups	Control	DM	DM + EL	DM + SM	DM + metformin
Triglyceride^#	55.86±4.69	110.94±14.32^∗	49.63±6.37^a	63.34±7.86^b	94.54±19.31
Total cholesterol^#	88.55±7.28	123.26±15.80^∗	95.15±10.88^a	86.75±13.64^b	106.78±12.54
HDL-C^#	55.86±4.66	27.44±8.27^∗	44.63±5.49^a	40.94±6.77^b	41.89±4.69
LDL-C^#	21.52±1.93	73.63±3.2^∗	40.59±4.37^a	33.14±5.86^b	45.99±5.64^c
VLDL-C^#	11.17±0.69	22.19±4.76^∗	9.93±1.3^a	12.67±1.01^b	18.90±2.31

#Units: mg/dL. Values are given as mean ± SEM from 6 rats in each group, ∗P < 0.005 compared to control and a, b, c compared to diabetic group.