Research Article

Microarray Analysis of mRNA and MicroRNA Expression Profile Reveals the Role of β-Sitosterol-D-glucoside in the Proliferation of Neural Stem Cell

Figure 4

Genic network analysis. (a) Genic network. The genic network was plotted by use of the search tool STRING and drawing tool cytoscape to understand the interacting genes. The genic network consists of the majority of the upregulated and downregulated genes. The integral network and its magnified image are shown on the left and right parts, respectively. IGF1 is indicated by an arrow. (b) Connectivity analysis on the network. The “hubs” of the gene nodes were determined by interaction count and value; thus, Bub1b, Cdc20, 1Plk1, Spp1, IGF1, Aurkb, and Ndc80 are the hub genes.
360302.fig.004a
(a)
360302.fig.004b
(b)