Protective Effect of Qiliqiangxin Capsule on Energy Metabolism and Myocardial Mitochondria in Pressure Overload Heart Failure Rats

<table>Serum lactate and free fatty acid content in all the six groups. (a) Serum lactate concentrations in the myocardium. (b) The content of serum free fatty acid in the myocardium. Rats were administered with vehicle (0.5% CMC-Na), QL (0.25 g/kg/d, 0.5 g/kg/d, 1 g/kg/d), or Captopril (6.25 mg/kg/d). <svg height="15.775" id="M22" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 75.449997 15.775" width="75.449997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, compared TAC group with Sham group; <svg height="13.95" id="M23" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,-0,0,-.017,14.65,13.688)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg>, compared respective dose group with TAC group; <svg height="13.8" id="M25" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 65.074997 13.8" width="65.074997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,.062,5.375)"><path d="M453 85l-2 -2h-420l-2 2l211 361h2z" id="x25B4"></path></g>
<g transform="matrix(.017,-0,0,-.017,6.425,13.525)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg>, <svg height="13.8" id="M26" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 70.800003 13.8" width="70.800003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,-0,0,-.017,12.15,13.525)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg>, compared QL respective dose group with Captopril group.</table>

Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Protective Effect of Qiliqiangxin Capsule on Energy Metabolism and Myocardial Mitochondria in Pressure Overload Heart Failure Rats 