Chinese Medicine Formula “Jian-Pi-Zhi-Dong Decoction” Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice

<table>MicroPET imaging and semiquantitative determination of ROI: Panel (A) represents coronal MicroPET imaging of bilateral striatum regions after an 8-week treatment. The images were acquired after tail vein injection of 1 mCi <sup>11</sup>C-<i>β</i>-CFT. (a) Saline group, (b) IDPN group, (c) IDPN+Tia group, and (d) IDPN+JPZDD group. Brighter areas revealed higher uptake ratio in brains. Panel (B) indicates ROI at bilateral striatum to cerebellum after <sup>11</sup>C-<i>β</i>-CFT uptake and tracing. <svg height="13.95" id="M23" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 73.300003 13.95" width="73.300003" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with IDPN group, <svg height="15.775" id="M24" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 75.449997 15.775" width="75.449997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with saline group, and <sup>▲</sup><svg height="11.375" id="M25" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with IDPN+Tia group.</table>

Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Chinese Medicine Formula “Jian-Pi-Zhi-Dong Decoction” Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice 

Figure 2 | Chinese Medicine Formula “Jian-Pi-Zhi-Dong Decoction” Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in Mice 