Persea americana Mill. Seed: Fractionation, Characterization, and Effects on Human Keratinocytes and Fibroblasts

Table 5

Regulation of NHDF gene expression after incubation for 6 h with 10 μg/mL avocado cotyledon methanol-water partition M and HSCCC fractions in minimal media. Gene expression of three independent tests was normalized to the endogenous control and to the target gene expression of untreated cells. A > 2-fold up- or downregulation has been considered as significant. Significant values are highlighted in bold letters; n.c.: a statistically firm calculation was not possible.

	EGFR	InsR	STAT6	SMAD3	Col1A2	FN1
Methanol-water partition M	1	1	1	1	1	2
M.2	8	7	4	4	10	5
M.3	1	1	1	1	2	1
M.6	1	2	1	0.5	2	3
M.7	n.c.	3	n.c.	n.c.	n.c.	6