Research Article

Antipoliovirus Activity of the Organic Extract of Eupatorium buniifolium: Isolation of Euparin as an Active Compound

Figure 5

Effect of addition of euparin on the PV-1 production during a one-step replication cycle. Vero cell monolayers were infected at m.o.i. = 5 and euparin (10 µg/mL) was added at different h p.i. (a) or min p.i. (b), after the adsorption period. At 8 h p.i. at 37°C, the extracellular PV-1 production was determined by the viral plaque assay. * versus 0 h p.i.; versus 0 min p.i.; versus 10 min p.i. # versus 0 h p.i.; versus 0 min p.i. versus 0 min p.i.; 10 min p.i.
402364.fig.005a
(a)
402364.fig.005b
(b)