Research Article

An Engineered Arginase FC Protein Inhibits Tumor Growth In Vitro and In Vivo

Figure 5

rhArg-Fc inhibits endothelial cell growth and migration. (a) Confluent HUVEC cells were wounded with a tip, washed and replaced with medium in the presence or absence of 0.5 IU/mL rhArg-Fc; images at 0 and 15 h were captured. (b) Confluent HUVEC cells were suspended in Matrigel in the presence or absence of rhArg-Fc; images were captured at 18 h.
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423129.fig.005b
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