Research Article

Chinese Medicine Formula Lingguizhugan Decoction Improves Beta-Oxidation and Metabolism of Fatty Acid in High-Fat-Diet-Induced Rat Model of Fatty Liver Disease

Figure 3

LGZG enhanced metabolism and transport of fatty acid through modulation of SREBP-1c, ACSL and ApoB100 expression. The relative mRNA and protein expression of SREBP-1c, ACSL, and ApoB100 were detected by real-time PCR and western blot. (a) The influence of LGZG and its decomposed recipes on the protein expression of hepatic SREBP-1c and ACSL; (b)–(d) the influence of LGZG and its decomposed recipes on the relative mRNA of hepatic SREBP-1c, ACSL, and ApoB100 (normalized by β-actin). versus normal group, versus model group.
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