Synergistic Inhibition of Angiogenesis by Artesunate and Captopril In Vitro and In Vivo

Figure 3

Quantification of vascularization in quail eggs maintained for 72 h was observed after incubation with 100 μg captopril or artesunate for 24 h. Both drugs significantly inhibited vascularization compared to DMSO (negative control) (Student’s t-test). The areas of fine capillaries were measured by a software routine described in Section 2.