Research Article

Synergistic Inhibition of Angiogenesis by Artesunate and Captopril In Vitro and In Vivo

Figure 9

Synergistic effect of artesunate and captopril in HUVEC monolayers in vitro. The closing of the wound was observed 5 h after scratching. Both drugs were mixed at different ratios as indicated, 100% mean IC50. If the effect is only additional, 50% inhibition is expected. Values above 50% indicate synergistic interaction, which was observed by the combination of both drugs.
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