Research Article

Aqueous Extract of Paeonia lactiflora and Paeoniflorin as Aggregation Reducers Targeting Chaperones in Cell Models of Spinocerebellar Ataxia 3

Figure 6

HSF1 overexpression in ATXN3/Q75-GFP transient cell models. HEK-293T cells were co-transfected with plasmids encoding ATXN3/Q75-GFP and plasmid with (+HSF1) or without (−HSF1) HSF1 cDNA. After 2 days, aggregation percentage was assessed by HCA system. (The scale bar = 50 μm). The percentage of aggregate formation counted among three random fields.
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