The Protective Effects of Cobra Venom from Naja naja atra on Acute and Chronic Nephropathy
Figure 9
The effects of NNAV on renal pathology in adriamycin-injected rats. Wistar rats were treated as described in the legend of Figure 1. At the end of the experiment, rats were killed and kidneys were dissected and fixed for electron microscopic examination. Morphological analysis of renal pathology was performed with a transmission electron microscopy. (a)–(e) represented control, model, and Naja naja atra venom in doses of 20, 40, and 80 μg/kg groups, respectively. It showed foot process effacement (arrows) in model group, but, in Naja naja atra venom-treated groups, the foot process lesions (arrows) were significantly reduced. Scale bars: (a) 2.5 μm; (b) 2 μm; (c) 2 μm; (d) 1 μm; (e) 0.5 μm, respectively.
