QiShenYiQi Pills, a Compound Chinese Medicine, Ameliorates Doxorubicin-Induced Myocardial Structure Damage and Cardiac Dysfunction in Rats

Table 1

Echocardiography parameters of rat hearts in different conditions.

GROUP	𝑛	LVIDd; (mm)	LVIDs; (mm)	LVPWd (mm)	LVPWs (mm)	EF (%)	FS (%)
Control 2W	6	7.468 ± 0.18	4.338 ± 0.14	1.985 ± 0.12	3.046 ± 0.06	71.03 ± 1.27	41.88 ± 1.07
DOX 2W	14	6.901 ± 0.023	4.985 ± 0.13*	1.372 ± 0.11*	1.780 ± 0.14*	51.68 ± 3.51*	27.49 ± 2.28*
Control 4W	4	7.654 ± 0.34	4.521 ± 0.21	1.873 ± 0.09	2.782 ± 0.07	69.73 ± 2.62	40.86 ± 2.27
DOX 4W + NS	6	7.624 ± 0.29	5.439 ± 0.29	1.395 ± 0.09^▲	2.111 ± 0.32^▲	53.52 ± 2.57^▲	28.78 ± 1.64^▲
DOX 4W + QSYQ	7	7.279 ± 0.10	4.106 ± 0.17^#	1.565 ± 0.06^#	2.428 ± 0.08^#	72.93 ± 2.37^#	43.60 ± 2.12^#

* 𝑃<0.05 versus Control 2W group; ^#𝑃<0.05 versus DOX 4W + NS group; ^▲𝑃<0.05 versus Control 4W group. LVIDd: left ventricular internal diameter at end-diastole; LVIDs: left ventricular internal diameters at end systole; LVPWd: left ventricular posterior wall at diastole; LVPWs: left ventricular posterior wall at systole; EF: left ventricle ejection fraction; FS: left ventricle fractional shortening. The data are presented as mean ± S.E. The treatments for each group are detailed in Section 2.