Research Article

A Methanol Extract of Brugmansia arborea Affects the Reinforcing and Motor Effects of Morphine and Cocaine in Mice

Figure 1

Means (±SEM) of locomotor activity (over six hours) in photocell cuts from adult mice treated with (a) physiological saline (Sal), 7.5, 15, 30, or 60 mg/kg of B. arborea (B7.5, B15, B30, and B60), and 40 mg/kg of morphine (M40) or (b) 40 mg/kg of morphine plus 7.5, 15, 30, or 60 mg/kg of B. arborea (M40 + B7.5, M40 + B15, M40 + B30, or M40 + B60). Differences with respect to mice treated with saline ; .
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(a)
482976.fig.001b
(b)