Evidence-Based Complementary and Alternative Medicine

Research Article

Neural Encoding of Acupuncture Needling Sensations: Evidence from a fMRI Study

Table 5

Summary of anatomic foci showing brain activity of tactile stimulation and positive and negative bold responses associated with the intensity of individual needling sensation ( corrected).
Atlas structure at the center
of maximum difference		 Mean fmri response to tactile PressureHeavinessFullnessTingling
 
Inferior frontal gyrus L        −531424−4.01−531424−4.01    
 R    56−2123.37        418123.02
Superior frontal gyrus L        −116221−2.91−116221−2.91    
 R20−263−3.20                
Precentral gyrus L−20−2663−2.86−565244.64            
 R35−2648−2.7856−5243.4435−2651−3.0535−2651−3.05    
Orbital gyri R1447−10−3.29                
Central sulcus L−38−2957−3.20                
 R38−2042−4.5556−5243.4432−2651−3.0232−2651−3.02    
Postcentral gyrus L−38−2957−3.20−59−17303.46            
 R47−1745−3.0150−17483.63            
Postcentral sulcus L−56−23303.31−56−20304.03            
 R26−3857−3.3053−20363.00            
Supramarginal gyrus L−62−26243.71−56−23303.72            
 R    56−29273.36            
Inf. insula L−32−2393.20−35−2393.79            
Ant. insula R29236−3.71322663.08        292363.08
Sup. insula R35−1421−3.53358153.02        3811153.55
Superior temporal gyrus L−478−19−3.62−508−43.55−62−2612−3.19−62−2612−3.19    
 R59−8−1−5.0265−32153.1862−86−3.3362−86−3.33    
Superior temporal sulcus L−475−19−3.99    −47−35−1−4.53−47−35−1−4.53    
 R59−11−1−4.84                
Middle temporal gyrus L−478−22−3.52                
 R442−25−3.68                
Parahippocampal gyrus L        −20−29−163.01−20−29−163.01−20−14−255.48
 L−32−17−22−2.95    −14−41−4−3.00−14−41−4−3.00−32−11−31−4.28
Hippocampus R32−26−13−5.38            29−26−133.86
Lingual gyrusL−2−83−7−3.02    −8−746−3.96−8−746−3.96    
Temporal pole L−475−28−3.07    −208−31−8.18−208−31−8.18−32−8−31−5.31
 R4711−25−3.0641−2−342.77            
Cerebellum cortex L        −8−77−313.38−8−77−313.38    
 L−2−53−31−3.08    −32−47−52−3.95−32−47−52−3.95    
 R2−50−31−3.2635−53−524.07            
Brain stem      −5−29−223.28            
is the value taken from the voxel with maximal signal change.
“−” means negative bold responses.
Inf. insula: inferior segment of the circular sulcus of the insula.
Ant. insula: anterior segment of the circular sulcus of the insula.
Sup. insula: superior segment of the circular sulcus of the insula.