Research Article
Identification of Target Genes Involved in the Antiproliferative Effect of Enzyme-Modified Ginseng Extract in HepG2 Hepatocarcinoma Cell
Table 3
Genes with highly upregulated expression due to EMGE in HepG2.
| | Symbol | Gene description | Fold change | GenBank ID |
| | CYP1A1 | Cytochrome P450, family 1, subfamily A | 20.0 | NM000499 | | HGD | Homogentisate 1,2-dioxygenase | 15.3 | NM000187 | | AQP3 | Aquaporin 3 | 14.5 | NM004925 | | IL8 | Interleukin 8 | 14.3 | NM000584 | | ANXA2 | Annexin A2 | 11.1 | NM001002857 | | HSPA9 | Heat shock 70 kDa protein 9 | 10.5 | NM004134 | | CASP4 | Caspase-4 | 10.4 | NM001225 | | SMAD2 | SMAD family member 2 | 9.8 | NM001003652 | | MAPK6 | Mitogen-activated protein kinase 6 | 9.3 | NM002748 | | KLF6 | Kruppel-like factor 6 | 9.0 | NM001160124 | | CTNNB1 | Catenin (cadherin-associated protein), beta 1, 88 kda | 8.3 | NM001098209 | | AIFM1 | Apoptosis-inducing factor, mitochondrion-associated, 1 | 7.8 | NM001130846 | | PPHLN1 | Periphilin 1 | 7.5 | NM001143787 | | UQCRC2 | Ubiquinol-cytochrome c reductase core protein II | 7.4 | NM003366 | | IL6ST | Interleukin 6 signal transducer | 6.4 | NM001190981 | | IFITM1 | Interferon-induced transmembrane protein 1 | 5.1 | NM003641 | | CASP7 | Caspase-7 | 5.0 | NM001227 |
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