Research Article
Identification of Target Genes Involved in the Antiproliferative Effect of Enzyme-Modified Ginseng Extract in HepG2 Hepatocarcinoma Cell
Table 4
Genes with highly downregulated expression due to EMGE in HepG2.
| | Symbol | Gene description | Fold change | GenBank ID |
| | CDCA3 | Cell division cycle associated 3 | −8.4 | NM031299 | | CS | Citrate synthase | −8.0 | NM004077 | | CDCA8 | Cell division cycle associated 8 | −7.7 | NM018101 | | CABLES2 | Cdk5 and Abl enzyme substrate 2 | −7.4 | NM031215 | | CDC25B | Cell division cycle 25 homolog B | −6.6 | NM004358 | | CNNM3 | Cyclin M3 | −6.2 | NM017623 | | ZNF362 | Zinc finger protein 362 | −5.8 | NM152493 | | CCNK | Cyclin K | −5.8 | NM001099402 | | RAD51AP1 | RAD51 associated protein 1 | −5.8 | NM001130862 | | LEAP2 | Liver expressed antimicrobial peptide 2 | −5.3 | NM052971 | | HEPACAM | Hepatocyte cell adhesion molecule | −5.1 | NM152722 | | ALDH3B1 | Aldehyde dehydrogenase 3 family, member B1 | −5.0 | NM000694 | | NPRL3 | Nitrogen permease regulator-like 3 | −5.0 | NM001039476 | | DOT1L | DOT1-like, histone H3 methyltransferase | −5.0 | NM032482 |
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