About this Journal Submit a Manuscript Table of Contents
Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 509134, 7 pages
http://dx.doi.org/10.1155/2013/509134
Research Article

Metabonomics-Based Study of Clinical Urine Samples in Suboptimal Health with Different Syndromes

School of Pre-Clinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China

Received 18 September 2012; Revised 2 December 2012; Accepted 2 December 2012

Academic Editor: William C. S. Cho

Copyright © 2013 Hai-Zhen Cui et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. X. Wang, Sub-Optimal Health: New Concept of Health in 21st Century, Jiangxi Science & Technology Press, Jiangxi, China, 2002.
  2. J. Pang, H. L. Tang, and Y. Yang, “Epidemiological survey of Chinese medical syndrome distribution in some cities of Guangxi: 1467 cases of chronic fatigue syndrome,” Guangxi Journal of TCM, vol. 31, no. 1, pp. 9–11, 2008.
  3. Y. L. Wei, J. Kong, G. L. Liu, et al., “Exploration on type and feature of traditional Chinese medicine syndrome in 205 cases of general hospital employees with sub-optimal health status,” China Journal of TCM and Pharmacy, vol. 23, no. 2, pp. 107–110, 2008.
  4. K. Akira, H. Mitome, M. Imachi, Y. Shida, H. Miyaoka, and T. Hashimoto, “LC-NMR identification of a novel taurine-related metabolite observed in 1H NMR-based metabonomics of genetically hypertensive rats,” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 5, pp. 1091–1096, 2010. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Holmes, T. M. Tsang, and S. J. Tabrizi, “The application of NMR-based metabonomics in neurological disorders,” NeuroRx, vol. 3, no. 3, pp. 358–372, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. Q. N. Van, J. R. Klose, D. A. Lucas et al., “The use of urine proteomic and metabonomic patterns for the diagnosis of interstitial cystitis and bacterial cystitis,” Disease Markers, vol. 19, no. 4-5, pp. 169–183, 2003. View at Scopus
  7. M. S. Hodavance, S. L. Ralston, and I. Pelczer, “Beyond blood sugar: the potential of NMR-based metabonomics for type 2 human diabetes, and the horse as a possible model,” Analytical and Bioanalytical Chemistry, vol. 387, no. 2, pp. 533–537, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. M. A. Constantinou, E. Papakonstantinou, M. Spraul et al., “1H NMR-based metabonomics for the diagnosis of inborn errors of metabolism in urine,” Analytica Chimica Acta, vol. 542, no. 2, pp. 169–177, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. J. E. Ippolito, M. E. Merrit, F. Bäckhed et al., “Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers,” Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 33, pp. 12505–12510, 2006. View at Publisher · View at Google Scholar · View at Scopus
  10. H. G. Luo, J. X. Chen, Q. Zhang et al., “Comparative study on effects of Xiaoyao powder and its modified prescription on plasma metabolomics of rats with chronic immobilization stress,” Chinese Journal of Integrative Medicine, vol. 2012, p. 6, 2012. View at Publisher · View at Google Scholar
  11. Y. F. Zhu and T. B. Zhang, “Metabonomics in research applications toxicology,” Foreign Medical Sciences, vol. 32, no. 3, p. 156, 2005.
  12. J. Y. Zhao, X. Z. Yan, and S. Q. Peng, “Metabonomics study on nephrotoxicity of Aristolochia manshuriensis,” Chinese Traditional and Herbal Drugs, vol. 37, no. 5, pp. 725–730, 2006. View at Scopus
  13. H. G. Luo, J. Ding, G. X. Yue, and J. X. Chen, “Metabonomic study of syndrome of liver qi stagnation and spleen deficiency in rats,” Journal of Chinese Integrative Medicine, vol. 5, no. 3, pp. 307–313, 2007. View at Scopus
  14. H. Zhao, W. H. Xiong, X. Zhao, L. M. Wang, and J. X. Chen, “Development and evaluation of a traditional Chinese medicine syndrome questionnaire for measuring sub-optimal health status in China,” Journal of Traditional Chinese Medicine, vol. 32, no. 2, pp. 129–136, 2012.
  15. L. M. Wang, X. Zhao, X. L. Wu et al., “Diagnosis analysis of 4 TCM patterns in sub-optimal health status: a structural equation modelling approach,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 970985, 6 pages, 2012. View at Publisher · View at Google Scholar
  16. N. J. Waters, C. J. Waterfield, R. D. Farrant, E. Holmes, and J. K. Nicholson, “Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity,” Chemical Research in Toxicology, vol. 18, no. 4, pp. 639–654, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. J. C. Lindon, J. K. Nicholson, E. Holmes, and J. R. Everett, “Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids,” Concepts in Magnetic Resonance, vol. 12, no. 5, pp. 289–320, 2000. View at Scopus
  18. J. Balkan, O. Kanbağli, G. Aykaç-Toker, and M. Uysal, “Taurine treatment reduces hepatic lipids and oxidative stress in chronically ethanol-treated rats,” Biological and Pharmaceutical Bulletin, vol. 25, no. 9, pp. 1231–1233, 2002. View at Publisher · View at Google Scholar · View at Scopus
  19. J. X. Chen, W. Li, X. Zhao, and J. X. Yang, “Effects of the Chinese traditional prescription Xiaoyaosan decoction on chronic immobilization stress-induced changes in behavior and brain BDNF, TrkB, and NT-3 in rats,” Cellular and Molecular Neurobiology, vol. 28, no. 5, pp. 745–755, 2008.
  20. S. X. Wang, J. X. Chen, G. X. Yue, M. H. Bai, M. J. Kou, and Z. Y. Jin, “Xiaoyaosan decoction regulates changes in neuropeptide Y and leptin receptor in the rat arcuate nucleus after chronic immobilization stress,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 381278, 16 pages, 2012. View at Publisher · View at Google Scholar
  21. Z. Z. Meng, J. H. Hu, J. X. Chen, and G. X. Yue, “Xiaoyaosan decoction, a traditional Chinese medicine, inhibits oxidative-stress-induced hippocampus neuron apoptosis in vitro,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 489254, 8 pages, 2012. View at Publisher · View at Google Scholar
  22. J. X. Chen, B. Ji, Z. L. Lu, and L. S. Hu, “Effects of Chai Hu (Radix Burpleuri) containing formulation on plasma β-endorphin, epinephrine and dopamine in patients,” The American Journal of Chinese Medicine, vol. 33, no. 5, pp. 737–745, 2005.