A Systems Biology Approach to Characterize Biomarkers for Blood Stasis Syndrome of Unstable Angina Patients by Integrating MicroRNA and Messenger RNA Expression Profiling

Figure 7

The PPIs network of downregulated mRNAs of the miRNA/mRNA interactive network. Rectangular represented downregulated mRNAs and round represented added interactive mRNAs. The interactions between two mRNAs extracted from pathways were shown as solid lines while those predicted interactions were shown as dashed lines. Extracted interactions involved in activation, expression regulation, or catalysis were shown with an arrowhead on the end of the line, while interactions involved in inhibition were shown with a “T” bar.