A Systems Biology Approach to Characterize Biomarkers for Blood Stasis Syndrome of Unstable Angina Patients by Integrating MicroRNA and Messenger RNA Expression Profiling

Table 4

Clinical characteristics of subjects of microarray analysis.

	UA with BSS (𝑛=5)	Controls (𝑛=5)	𝑃 value
Male gender (𝑛)	3 (60%)	3 (60%)
Age (years)	61.60±4.93	61.00±4.36	0.596
BMI (kg/m^2)	23.18±3.89	23.24±1.62	0.975
Active smoker (𝑛)	1 (20%)	1 (20%)
BSS grades	72.80±10.47	0
Number of vessels (𝑛)	3.40±0.89	0
Hypertension (𝑛)	4 (80%)	0	0.048
Type 2 diabetes mellitus (𝑛)	0	0
Total cholesterol (mmol/L)	3.96±1.45	4.02±0.79	0.347
LDL cholesterol (mmol/L)	2.33±1.01	2.51±0.60	0.743
HDL cholesterol (mmol/L)	1.33±0.35	1.30±0.30	0.874
Triglycerides (mmol/L)	1.15±0.50	1.09±0.34	0.815
CRP (mg/L)	3.64±3.25	0.94±0.09	0.018
Concurrent medication (𝑛)
Antiplatelet	100%	0	0.008
Beta-blocker	4 (80%)	0	0.048
ACEI/ARB	4 (80%)	0	0.048
Calcium-channel blockers	3 (60%)	0	0.167
Nitrates	4 (80%)	0	0.048
Statin	4 (80%)	0	0.048

Data represents means ± SEM. Abbreviations: ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; BMI: body mass index; BSS: blood stasis syndrome; HDL: high-density protein; CRP: C-reactive protein; LDL: low-density protein.