Gastrodin Protects Apoptotic Dopaminergic Neurons in a Toxin-Induced Parkinson’s Disease Model

Figure 2

Effect of gastrodin on DPPH (a) and alkyl (b) free radical scavenging activities. Gastrodin prevented the ROS generation in 1 mM MPP⁺-treated SH-SY5Y cells as measured by fluorometric analysis using DCFH-DA (c). Gastrodin augmented the MPP⁺- and MPTP-induced perturbation in superoxide dismutase (SOD) activity in SH-SY5Y cells (d), striatum (e), and SNpC (f), respectively. Data are percentages of values in the untreated control cultures and are means ± standard errors of three independent experiments in triplicate. ^###𝑃<0.001 compared with the control group, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001 compared with the MPP⁺-treated group (one-way analysis of variance followed by Tukey’s post hoc test).

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